The Protective Effect of Recombinant Human Erythropoietin against Cisplatin-Induced Ototoxicity
نویسندگان
چکیده
Department of Otorhinolaryngology, Dokuz Eylul University School of Medicine, İzmir, Turkey (ED, YO, GK, EAG) Department of Laboratory of Animal Science, Dokuz Eylul University School of Medicine, İzmir, Turkey (EK, OY) Department of Basic Oncology, Dokuz Eylul University School of Medicine, İzmir, Turkey (PE, SA, ZA) Department of Biostatistics, Dokuz Eylul University School of Medicine, İzmir, Turkey (HE) Department of Physiology, Dokuz Eylul University School of Medicine, İzmir, Turkey (MK) Department of Histology, Dokuz Eylul University School of Medicine, İzmir, Turkey (AB)
منابع مشابه
Re: Sex differences in protective effect of recombinant human erythropoietin against cisplatin-induced nephrotoxicity in rats.
INTRODUCTION The protective role of recombinant human erythropoietin (RHE) against cisplatin-induced nephrotoxicity has been reported, but the role of sex differences is not clearly known. The aim of this study was to determine the sex-based difference in the protective effect of RHE against cisplatin-induced nephrotoxicity. MATERIALS AND METHODS Thirty-three Wistar rats were divided into 6 g...
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INTRODUCTION Cisplatin is one of the main chemotherapeutic agents used for the treatment of many types of cancer. However, ototoxicity, one of the most serious side effects of cisplatin, restricts its usage. OBJECTIVE We aimed to investigate the protective effects of whortleberry extract against cisplatin-induced ototoxicity by evaluating hearing and histopathological cochlear damage and by m...
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